Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment

Br J Dermatol. 2017 Dec;177(6):1745-1746. doi: 10.1111/bjd.15191. Epub 2017 Nov 6.
No abstract available

Publication types

  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Azathioprine / therapeutic use*
  • Dermatitis, Atopic / drug therapy*
  • Dermatitis, Atopic / genetics
  • Female
  • Filaggrin Proteins
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Intermediate Filament Proteins / genetics*
  • Loss of Function Mutation / genetics*
  • Male
  • Methotrexate / therapeutic use*
  • Middle Aged
  • Treatment Outcome

Substances

  • FLG protein, human
  • Filaggrin Proteins
  • Immunosuppressive Agents
  • Intermediate Filament Proteins
  • Azathioprine
  • Methotrexate