Tacrolimus in combination with methotrexate and corticosteroid for the treatment of child-onset anti-signal recognition particle antibody-positive necrotizing myopathy

MeSH terms

• Age of Onset
• Autoantibodies / blood
• Biopsy / methods
• Child
• Drug Administration Schedule
• Drug Therapy, Combination / methods
• Glucocorticoids / administration & dosage*
• Humans
• Male
• Methotrexate / administration & dosage*
• Muscle, Skeletal / pathology*
• Muscular Diseases* / diagnosis
• Muscular Diseases* / drug therapy
• Muscular Diseases* / immunology
• Muscular Diseases* / physiopathology
• Necrosis
• Signal Recognition Particle / immunology*
• Tacrolimus / administration & dosage*
• Treatment Outcome