Abstract
The United Kingdom is introducing a universal annual influenza vaccination programme for children. Live attenuated influenza vaccine (LAIV) effectiveness (VE) against laboratory-confirmed influenza hospitalisation in 2 to 6 year-olds in England was measured in 2015/16 using the screening method. VE adjusted for age, geography and month was 54.5% (95% confidence interval (CI): 31.5% to 68.4%) for all influenza types combined; 48.3% (95% CI: 16.9% to 67.8%) for A(H1N1)pdm09 and 70.6% (95% CI: 33.2% to 87.1%) for B. The findings support on-going programme roll-out.
Keywords:
LAIV; hospitalisation; influenza; vaccine effectiveness.
This article is copyright of The Authors, 2017.
MeSH terms
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Adolescent
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Case-Control Studies
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Child
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Child, Preschool
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Disease Outbreaks / prevention & control*
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England / epidemiology
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Female
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Hospitalization / statistics & numerical data*
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Humans
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Immunization Programs
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Influenza A Virus, H1N1 Subtype / immunology
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Influenza A Virus, H1N1 Subtype / isolation & purification*
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Influenza B virus / immunology
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Influenza B virus / isolation & purification
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Influenza Vaccines / administration & dosage
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Influenza Vaccines / immunology*
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Influenza, Human / epidemiology*
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Influenza, Human / immunology
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Influenza, Human / prevention & control*
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Laboratories
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Male
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Outcome Assessment, Health Care
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Seasons
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Vaccination / statistics & numerical data
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Vaccine Potency
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Vaccines, Attenuated / administration & dosage
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Vaccines, Attenuated / immunology*
Substances
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Influenza Vaccines
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Vaccines, Attenuated