Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015

Infection. 2017 Jun;45(3):349-354. doi: 10.1007/s15010-017-1008-1. Epub 2017 Mar 18.

Abstract

We conducted a retrospective observational study at four German university hospitals of patients with laboratory-confirmed influenza in 2014/2015. Overall, a fatality rate of 8% was observed. Significantly more A(H1N1)pdm09 patients were admitted to ICU compared to those with A(H3N2). However, fatal outcome was not significantly increased among A(H1N1)pdm09 cases. Nosocomial infections were seen in 17% of cases. Systematic collection of data from hospitals will complement national influenza surveillance.

Keywords: Epidemiology; Influenza; Nosocomial; Observational study; University hospital.

MeSH terms

  • Adult
  • Aged
  • Cross Infection / epidemiology*
  • Cross Infection / virology*
  • Female
  • Germany / epidemiology
  • Hospitals, University
  • Humans
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza A Virus, H1N1 Subtype / physiology*
  • Influenza A Virus, H3N2 Subtype / isolation & purification
  • Influenza A Virus, H3N2 Subtype / physiology*
  • Influenza, Human / epidemiology*
  • Influenza, Human / virology*
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies