Software for genome mapping by fingerprinting techniques

Comput Appl Biosci. 1988 Mar;4(1):125-32. doi: 10.1093/bioinformatics/4.1.125.

Abstract

A genome mapping package has been developed for reading and assembling data from clones analysed by restriction enzyme fragmentation and polyacrylamide gel electrophoresis. The package comprises: data entry; matching; assembly; statistical analysis; modelling. Data entry can be either manual or by a semiautomatic system based on a scanning densitometer. The primary emphasis in the analytical routines is on flexibility and interactive convenience, so that the operator has full knowledge of and control over the growing map, but a variety of automatic options are included. The package continually grows to meet the needs of the Caenorhabditis project.

MeSH terms

  • Base Sequence
  • Chromosome Mapping*
  • Cloning, Molecular
  • DNA / genetics
  • DNA / isolation & purification
  • DNA Restriction Enzymes
  • Database Management Systems
  • Electrophoresis, Polyacrylamide Gel
  • Software*

Substances

  • DNA
  • DNA Restriction Enzymes