Postrandomization Confounding Challenges the Applicability of Randomized Clinical Trials in Comparative Effectiveness Research

Affiliations

• ¹ Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, Beijing 100045; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing 100045, China.
• ² Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
• ³ Center for Medical Safety and Risk Administration, National Institute of Hospital Administration, Beijing 100091, China.