Dual phase cone-beam computed tomography in detecting <3 cm hepatocellular carcinomas during transarterial chemoembolization

J Cancer Res Ther. 2017 Jan-Mar;13(1):38-43. doi: 10.4103/0973-1482.206242.

Abstract

Objective: The objective of this study was to evaluate the sensitivity of dual phase cone-beam computed tomography (CBCT) in detecting small (<3 cm in diameter) hepatocellular carcinoma (HCC) tumors during transarterial chemoembolization (TACE).

Materials and methods: Twenty-two consecutive patients with unresectable small HCCs in whom TACE was performed were retrospectively evaluated. Contrast CT or contrast magnetic resonance imaging (MRI) was performed in all patients within 1 month prior to the procedure. Dual phase CBCT was performed prior to TACE and lipiodol-CBCT was performed after treatment. The sensitivity of dual phase CBCT in detecting small HCCs was compared to hepatic angiography, contrast enhanced CT and MRI.

Results: Seventy HCC tumors with sizes of P < 0.001).

Conclusions: Dual phase CBCT is significantly more sensitive than hepatic angiography, contrast enhanced CT, and MRI in detecting smaller than 3 cm HCC tumors and can be a helpful modality in making accurate planning for treatment of HCC.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / diagnostic imaging*
  • Carcinoma, Hepatocellular / pathology
  • Chemoembolization, Therapeutic*
  • Cone-Beam Computed Tomography*
  • Contrast Media / administration & dosage
  • Ethiodized Oil / administration & dosage
  • Female
  • Humans
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / pathology
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Retrospective Studies

Substances

  • Contrast Media
  • Ethiodized Oil