Alopecia Areata: An Update on Treatment Options for Children

Paediatr Drugs. 2017 Oct;19(5):411-422. doi: 10.1007/s40272-017-0239-z.

Abstract

Pediatric alopecia areata is a spectrum of autoimmune non-scarring alopecia in which some patients lose small patches of hair from their scalp but others lose more or all of the hair from the scalp and body, including eyebrows and eyelashes. Few studies have looked at therapies for this disorder in children, so much of the data are derived from adult literature and describe off-label use of medication. Generally, topical therapies consisting of topical steroids and topical irritating compounds/contact sensitizers are used. Systemic therapies that block the immune system, including Janus kinase (JAK) inhibitors, have also been used in this disease. This paper reviews the data on therapy for alopecia areata in pediatric patients.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Alopecia Areata / drug therapy*
  • Alopecia Areata / epidemiology
  • Alopecia Areata / psychology
  • Child
  • Drug Administration Routes
  • Humans
  • Off-Label Use

Substances

  • Adrenal Cortex Hormones