[Neonatal hyperthyroidism: A sometimes challenging diagnosis]

Arch Pediatr. 2017 Jul;24(7):622-624. doi: 10.1016/j.arcped.2017.04.012. Epub 2017 Jun 3.
[Article in French]

Abstract

Graves disease complicates two pregnancies out of 1000 and when it is known before pregnancy, it warrants careful monitoring of the fetus and the newborn. We report on a case of neonatal hyperthyroidism, which revealed a previously unknown maternal thyroid disease. In this situation, neonatal signs can be misinterpreted, delaying the diagnosis. Neonatal hyperthyroidism is, however, a therapeutic emergency because of the risk of cardiac and neurological complications. The neonatologist must identify thyroid disease in the absence of a maternal history in order to promptly start therapy.

Publication types

  • Case Reports

MeSH terms

  • Cholinesterase Inhibitors / therapeutic use
  • Goiter / diagnosis*
  • Goiter / surgery*
  • Humans
  • Hyperthyroidism / etiology*
  • Hyperthyroidism / therapy
  • Infant, Newborn
  • Male
  • Myasthenia Gravis, Neonatal / diagnosis*
  • Myasthenia Gravis, Neonatal / therapy
  • Pyridostigmine Bromide / therapeutic use
  • Respiratory Distress Syndrome, Newborn / etiology
  • Thyroidectomy

Substances

  • Cholinesterase Inhibitors
  • Pyridostigmine Bromide