Ductal stones recurrence after extracorporeal shock wave lithotripsy for difficult common bile duct stones: Predictive factors

Dig Liver Dis. 2017 Oct;49(10):1128-1132. doi: 10.1016/j.dld.2017.05.010. Epub 2017 May 23.

Abstract

Background & purpose: Extra-corporeal shock wave lithotripsy (ESWL) can be considered in difficult common bile duct stones (DCBDS), with a success rate greater than 90% but data on stone recurrence after ESWL are limited. We performed a retrospective analysis to evaluate long-term outcomes in patients who underwent ESWL for DCBDS.

Methods: From May 1992 to October 2012, patients who underwent ESWL treatment for DCBDS, not amenable to endoscopic extraction, were included. Data on long-term outcome were collected through phone interviews and medical records.

Results: A total of 201 patients with a successful clearance of DCBDS after ESWL were included. During a median follow-up period of 4.64 years, 40 patients (20%) developed a recurrence of bile duct stones. Logistic regression analysis showed that the common bile duct diameter, gallstones presence and the maximum stone size were significantly associated with recurrence.

Conclusions: We observed a recurrence rate of 20% over a median follow-up of 4 years. Gallbladder stones, stone size and a dilated common bile duct diameter are risk factors for recurrent stone formation, while ursodeoxycholic acid treatment did not influence recurrence in our population.

Keywords: Bile duct stone recurrence; Cholelithiasis; Extracorporeal shock wave lithotripsy; Ursodeoxycholic acid.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Common Bile Duct / pathology*
  • Female
  • Follow-Up Studies
  • Gallstones / pathology
  • Gallstones / therapy*
  • Humans
  • Lithotripsy*
  • Male
  • Middle Aged
  • Organ Size
  • ROC Curve
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Time Factors