Double the Trouble When Herpesviruses Join Hands

Un Yung Choi; Angela Park; Jae U Jung

doi:10.1016/j.chom.2017.06.016

Double the Trouble When Herpesviruses Join Hands

Cell Host Microbe. 2017 Jul 12;22(1):5-7. doi: 10.1016/j.chom.2017.06.016.

Authors

Un Yung Choi¹, Angela Park¹, Jae U Jung²

Affiliations

¹ Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
² Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: jaeujung@med.usc.edu.

Abstract

KSHV is the etiologic agent of PEL-an aggressive lymphoma. Interestingly, EBV concurrently exists in nearly 70% of PEL cases. In this issue of Cell Host & Microbe, McHugh et al. (2017) develop humanized mouse models for EBV/KSHV co-infection and identify their complementary effect on in vivo tumor formation.

MeSH terms

Animals
Coinfection*
Disease Models, Animal
Epstein-Barr Virus Infections / virology
Gene Expression Regulation, Viral
HIV / pathogenicity
HIV Infections / virology
Herpesviridae / pathogenicity*
Herpesviridae Infections / virology
Herpesvirus 4, Human / pathogenicity
Herpesvirus 8, Human / pathogenicity*
Humans
Lymphoma / virology
Lymphoma, Primary Effusion / virology
Mice
Sarcoma, Kaposi / virology

Abstract

MeSH terms

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