To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.
Keywords: PCR; endogenous virus; serology; transfusion.
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.