Genome Sequences of Seven Foot-and-Mouth Disease Virus Isolates Collected from Serial Samples from One Persistently Infected Carrier Cow in Vietnam

Steven J Pauszek; Miranda R Bertram; Le T Vu; Ethan J Hartwig; George R Smoliga; Barbara Brito; Carolina Stenfeldt; Kimberley VanderWaal; Ian H Fish; Vo V Hung; Nguyen T Phuong; Bui H Hoang; Luis L Rodriguez; Do H Dung; Jonathan Arzt

doi:10.1128/genomeA.00849-17

Genome Sequences of Seven Foot-and-Mouth Disease Virus Isolates Collected from Serial Samples from One Persistently Infected Carrier Cow in Vietnam

Genome Announc. 2017 Aug 24;5(34):e00849-17. doi: 10.1128/genomeA.00849-17.

Authors

Steven J Pauszek¹, Miranda R Bertram^{1

2}, Le T Vu³, Ethan J Hartwig¹, George R Smoliga¹, Barbara Brito^{1

2}, Carolina Stenfeldt^{1

3}, Kimberley VanderWaal³, Ian H Fish^{1

2}, Vo V Hung⁴, Nguyen T Phuong⁴, Bui H Hoang⁴, Luis L Rodriguez¹, Do H Dung⁵, Jonathan Arzt⁶

Affiliations

¹ Foreign Animal Disease Research Unit, Plum Island Animal Disease Center, ARS, USDA, Orient Point, New York, USA.
² Oak Ridge Institute for Science and Education, PIADC Research Participation Program, Oak Ridge, Tennessee, USA.
³ STEMMA Laboratory, Veterinary Population Medicine, University of Minnesota, St. Paul, Minnesota, USA.
⁴ Regional Animal Health Office No. 6, Department of Animal Health, Ministry of Agriculture and Rural Development, Ho Chi Minh City, Vietnam.
⁵ Department of Animal Health, Ministry of Agriculture and Rural Development, Hanoi, Vietnam.
⁶ Foreign Animal Disease Research Unit, Plum Island Animal Disease Center, ARS, USDA, Orient Point, New York, USA jonathan.arzt@ars.usda.gov.

Abstract

Several foot-and-mouth disease virus (FMDV) carrier cattle were identified in Vietnam by the recovery of infectious virus from oropharyngeal fluid. This report contains the first near-complete genome sequences of seven viruses from sequential samples from one carrier animal collected over the course of 1 year. The characterization of within-host viral evolution has implications for FMDV control strategies.