Human Embryo Editing: Opportunities and Importance of Transnational Cooperation

Duanqing Pei; David W Beier; Ephrat Levy-Lahad; Gary Marchant; Janet Rossant; Juan Carlos Izpisua Belmonte; Robin Lovell-Badge; Rudolf Jaenisch; Alta Charo; David Baltimore

doi:10.1016/j.stem.2017.09.010

Human Embryo Editing: Opportunities and Importance of Transnational Cooperation

Cell Stem Cell. 2017 Oct 5;21(4):423-426. doi: 10.1016/j.stem.2017.09.010.

Authors

Affiliations

¹ Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing; Organizing Committee for the International Summit on Human Gene Editing. Electronic address: pei_duanqing@gibh.ac.cn.
² Bay City Capital, San Francisco, CA 94111, USA; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
³ Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
⁴ Sandra Day O'Connor College of Law, Arizona State University, Phoenix, AZ 85004-4467, USA; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
⁵ Hospital for Sick Children, University of Toronto, Toronto, M5G 1X8, Canada; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
⁶ Salk Institute for Biological Studies, La Jolla, CA 92037, USA; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
⁷ The Francis Crick Institute, London NW1 1AT, UK; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing; Organizing Committee for the International Summit on Human Gene Editing.
⁸ Massachusetts Institute of Technology, Cambridge, MA 02142, USA; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
⁹ The University of Wisconsin Law School, Madison, WI 53706, USA; National Academies of Sciences and Medicine Consensus Study Committee on Human Genome Editing.
¹⁰ California Institute of Technology, Pasadena, CA 91125, USA; Organizing Committee for the International Summit on Human Gene Editing.

PMID: 28985523
DOI: 10.1016/j.stem.2017.09.010

Abstract

A recent National Academies report articulates a path forward for research, ethics, and governance of clinical applications involving genome editing. In light of recent human embryo editing developments, scientists and stakeholders from all nations should cooperate to take advantage of this historic opportunity for medicine and also basic human biology.

MeSH terms

Embryo, Mammalian / metabolism*
Gene Editing*
Genome, Human
Humans
International Cooperation*
Mutation / genetics

Grants and funding

MC_U117562207/MRC_/Medical Research Council/United Kingdom