All for One, and One for All

Eiru Kim; Traver Hart

doi:10.1016/j.cels.2017.10.005

All for One, and One for All

Cell Syst. 2017 Oct 25;5(4):314-316. doi: 10.1016/j.cels.2017.10.005.

Authors

Eiru Kim¹, Traver Hart²

Affiliations

¹ Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
² Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: traver@hart-lab.org.

PMID: 29073370
DOI: 10.1016/j.cels.2017.10.005

Abstract

Hemizygous deletion of a gene in tumor cells frequently causes reduced expression of its encoded mRNA and protein, as well as reduced protein-but not mRNA-expression of other members in the same protein complex.

Publication types

Comment

MeSH terms

Breast Neoplasms*
Humans
RNA, Messenger
Sequence Deletion

Substances

RNA, Messenger