License to kill: IFN-λ regulates antifungal activity of neutrophils

Sci Immunol. 2017 Nov 17;2(17):eaap9614. doi: 10.1126/sciimmunol.aap9614. Epub 2017 Nov 17.

Authors

Daniel Schnepf^{1

2}, Peter Staeheli³

Affiliations

¹ Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany.
² Spemann Graduate School of Biology and Medicine, Albert Ludwigs University Freiburg, Freiburg, Germany.
³ Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany. peter.staeheli@uniklinik-freiburg.de.

PMID: 29150440
DOI: 10.1126/sciimmunol.aap9614

Abstract

Interferon-λ mediates antifungal immunity by stimulating neutrophils to generate reactive oxygen species.

Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Publication types

Comment

MeSH terms

Antifungal Agents*
Immunity, Innate
Interferon Lambda
Interferons*
Neutrophils

Substances

Antifungal Agents
Interferons
Interferon Lambda