[A case of subarachnoid hemorrhage due to infective endocarditis by methicillin-resistant coagulase-negative staphylococcus]

Rinsho Shinkeigaku. 2017 Dec 27;57(12):775-777. doi: 10.5692/clinicalneurol.cn-001053. Epub 2017 Nov 28.
[Article in Japanese]

Abstract

A 77-year-old man visited our hospital with unstable gait following 2 months of anorexia. Brain MRI showed multiple infarcts; cardiac echocardiography revealed mitral-valve vegetation; and blood culture revealed methicillin-resistant coagulase-negative staphylococci. The patient was diagnosed with infective endocarditis (IE). Subarachnoid hemorrhage (SAH) developed ten days after antibiotic treatment. Intracranial aneurysm was not found. We speculated that chronic inflammation of the cerebral arterial walls by bacteria of low virulence was associated with SAH complication. The vegetation disappeared following additional gentamicin administration and the patient recovered to walk.

Keywords: MRCNS; infective endocarditis; mycotic aneurysm; subarachnoid hemorrhage; vegetation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Ceftriaxone / administration & dosage
  • Echocardiography, Transesophageal
  • Endocarditis / complications*
  • Endocarditis / diagnostic imaging
  • Endocarditis / drug therapy
  • Endocarditis / microbiology*
  • Gentamicins / administration & dosage
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Methicillin-Resistant Staphylococcus aureus*
  • Staphylococcal Infections*
  • Subarachnoid Hemorrhage / diagnostic imaging
  • Subarachnoid Hemorrhage / etiology*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vancomycin / administration & dosage

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Vancomycin
  • Ceftriaxone