Advanced Pediatric Neurosonography Techniques: Contrast-Enhanced Ultrasonography, Elastography, and Beyond

J Neuroimaging. 2018 Mar;28(2):150-157. doi: 10.1111/jon.12492. Epub 2017 Dec 27.

Abstract

Recent technical advances in neurosonography continue broadening the diagnostic utility, sensitivity, and specificity of ultrasound for detecting intracranial abnormalities bed side. The clinical and functional applications of neurosonography have significantly expanded since the 1980s when transcranial Doppler sonography first allowed anatomic and hemodynamic delineation of the intracranial vessels through the thin temporal skull. In the past few years, contrast-enhanced ultrasonography, elastography, 3D/4D reconstruction tools, and high-resolution microvessel imaging techniques have further enhanced the diagnostic significance of neurosonography. Given these advances, a thorough familiarity with these new techniques and devices is crucial for a successful clinical application allowing improved patient care. It is essential that future neurosonography studies compare these advanced techniques against the current "gold standard" computed tomography and magnetic resonance imaging to assure the accuracy of their diagnostic potential. This review will provide a comprehensive update on currently available advanced neurosonography techniques.

Keywords: Sonography; contrast-enhanced ultrasound; elastography.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain / diagnostic imaging*
  • Child
  • Contrast Media
  • Elasticity Imaging Techniques
  • Humans
  • Magnetic Resonance Imaging
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed
  • Ultrasonography / methods*
  • Ultrasonography, Doppler, Transcranial / methods

Substances

  • Contrast Media