Phase Angle as a Sarcopenia Marker in Hospitalized Elderly Patients

Nutr Clin Pract. 2018 Apr;33(2):232-237. doi: 10.1002/ncp.10016. Epub 2018 Feb 3.

Abstract

Background: Phase angle (PhA) has been proposed as a parameter to predict clinical outcomes and mortality for various diseases. Several studies have considered it an important nutrition assessment tool. However, the usefulness of this parameter as a sarcopenia marker has not yet been evaluated. This study was developed to evaluate the performance of PhA as a sarcopenia marker in hospitalized elderly patients.

Materials and methods: This was a cross-sectional study involving elderly patients admitted to a hospital in northeastern Brazil. The PhA was obtained from resistance and reactance measurements by bioelectrical impedance. Sarcopenia was defined as a decrease in muscle mass associated with a reduced muscle strength or physical performance.

Results: The sample consisted of 148 patients with a mean age of 71.6 (±7.6) years and a 62.8% prevalence of sarcopenia. The average PhA was 5.9 ± 2.0°, similar for men and women (5.9 ± 2.3 vs 5.9 ± 1.8; P = .946). In men, sarcopenic patients had a lower average PhA (5.6 ± 2.3°) when compared with patients without this condition (6.8 ± 1.9°; P = .024). When comparing the value of PhA regarding the degree of sarcopenia, it was found that patients from both sexes with severe sarcopenia had lower averages. The PhA had a low predictive capacity in relation to the diagnostic components of sarcopenia (physical performance, muscle mass, and strength).

Conclusion: PhA was an inaccurate marker to identify sarcopenia and presented low predictive capacity to explain muscle mass, muscle strength, and functional capacity, components involved in the diagnosis of sarcopenia.

Keywords: aged; body composition; elderly; electric impedance; phase angle; sarcopenia.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Aging*
  • Asymptomatic Diseases* / epidemiology
  • Biomarkers
  • Brazil / epidemiology
  • Cross-Sectional Studies
  • Electric Impedance
  • Female
  • Geriatric Assessment*
  • Hospitals, Public
  • Hospitals, University
  • Humans
  • Male
  • Nutrition Assessment*
  • Predictive Value of Tests
  • Prevalence
  • Risk
  • Sarcopenia / diagnosis*
  • Sarcopenia / epidemiology
  • Sarcopenia / physiopathology
  • Severity of Illness Index
  • Sex Factors

Substances

  • Biomarkers