Nivolumab-induced new-onset seronegative rheumatoid arthritis in a patient with advanced metastatic melanoma: A case report and literature review

Ammar Haikal; E Borba; Taqui Khaja; Gary Doolittle; Paul Schmidt

doi:10.4103/ajm.AJM_127_17

Nivolumab-induced new-onset seronegative rheumatoid arthritis in a patient with advanced metastatic melanoma: A case report and literature review

Avicenna J Med. 2018 Jan-Mar;8(1):34-36. doi: 10.4103/ajm.AJM_127_17.

Authors

Ammar Haikal¹, E Borba², Taqui Khaja¹, Gary Doolittle³, Paul Schmidt⁴

Affiliations

¹ Department of Internal Medicine, University of Kansas Medical Center, Kansas, USA.
² Department of Orthopedic Surgery, Cajuru Hospital, Curitiba, Brazil.
³ Department of Oncology, University of Kansas Medical Center, Kansas, USA.
⁴ Department of Rheumatology, University of Kansas Medical Center, Kansas, USA.

Abstract

Immune-related adverse events have been reported in patients treated with anti-programmed death-1 receptor drugs such as nivolumab. We present a case of a new-onset seronegative rheumatoid arthritis in a patient with metastatic melanoma treated with nivolumab.

Keywords: Immune-related adverse event; immunotherapy; inflammatory arthropathy; nivolumab; rheumatoid arthritis.

Publication types

Case Reports