Disseminated abscesses due to Mycoplasma faucium in a patient with activated PI3Kδ syndrome type 2

Nerea Dominguez-Pinilla; Luis M Allende; Jérémie Rosain; Maria Del Carmen Gallego; Fernando Chaves; Caroline Deswarte; Esther Viedma; Jaime de Inocencio Arocena; Jesús Ruiz-Contreras; Jacinta Bustamante; Luis Ignacio Gonzalez-Granado

doi:10.1016/j.jaip.2018.02.014

Disseminated abscesses due to Mycoplasma faucium in a patient with activated PI3Kδ syndrome type 2

J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1796-1798.e2. doi: 10.1016/j.jaip.2018.02.014. Epub 2018 Mar 1.

Affiliations

¹ Pediatric Hematology & Oncology Unit, University Hospital Virgen de la Salud, Toledo, Spain; Research Institute Hospital 12 Octubre (i+12), Madrid, Spain.
² Immunology Department, University Hospital 12 de Octubre, Research Institute Hospital 12 Octubre (i+12), Madrid, Spain.
³ Study Center for Primary Immunodeficiencies, Assistance Publique Hôpitaux de Paris (APHP), Necker Children Hospital, Paris, France; Paris Descartes University, Imagine Institute, Sorbonne Paris Cité, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U-1163, Necker Hospital for Sick Children, Paris, France.
⁴ Pediatric Radiology, University Hospital 12 de Octubre, Madrid, Spain.
⁵ Microbiology Department, University Hospital 12 de Octubre, Research Institute Hospital 12 Octubre (i+12), Madrid, Spain.
⁶ Paris Descartes University, Imagine Institute, Sorbonne Paris Cité, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U-1163, Necker Hospital for Sick Children, Paris, France.
⁷ Pediatric Rheumatology Unit, University Hospital 12 de Octubre and Department of Pediatrics, Complutense University of Madrid Hospital 12 de Octubre, Madrid, Spain.
⁸ Immunodeficiencies Unit, Department of Pediatrics, University Hospital 12 de Octubre, Research Institute Hospital 12 Octubre (i+12), Complutense University of Madrid, Madrid, Spain.
⁹ Study Center for Primary Immunodeficiencies, Assistance Publique Hôpitaux de Paris (APHP), Necker Children Hospital, Paris, France; Paris Descartes University, Imagine Institute, Sorbonne Paris Cité, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U-1163, Necker Hospital for Sick Children, Paris, France; St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
¹⁰ Immunodeficiencies Unit, Department of Pediatrics, University Hospital 12 de Octubre, Research Institute Hospital 12 Octubre (i+12), Complutense University of Madrid, Madrid, Spain. Electronic address: luisignacio.gonzalez@salud.madrid.org.

PMID: 29486251
DOI: 10.1016/j.jaip.2018.02.014

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Abscess
Adolescent
Agammaglobulinemia
Ascitic Fluid
Child
Class I Phosphatidylinositol 3-Kinases
Doxycycline / therapeutic use
Drug Therapy, Combination
Female
Humans
Immunologic Deficiency Syndromes / diagnosis*
Immunologic Deficiency Syndromes / drug therapy
Kidney / diagnostic imaging
Kidney / pathology*
Levofloxacin / therapeutic use
Lymphadenitis
Magnetic Resonance Imaging
Mycoplasma / physiology*
Mycoplasma Infections / diagnosis*
Mycoplasma Infections / drug therapy
Primary Immunodeficiency Diseases
RNA, Ribosomal, 16S / genetics*
Skin / pathology*

Substances

RNA, Ribosomal, 16S
Levofloxacin
Class I Phosphatidylinositol 3-Kinases
Doxycycline

Supplementary concepts

Activated PI3K-delta Syndrome