Abstract
Angiotensin (AT) II is an endogenous hormone that acts on venous and arterial smooth muscle to cause vasoconstriction. Recent trials have sparked great interest in its ability to be used as a vasopressor for catecholamine-refractory hypotension. Herein, we describe the successful use of AT II in a patient with a colonic perforation with septic shock refractory to conventional treatment. After AT II initiation, there was an immediate reduction in catecholamine requirement, and the patient survived.
MeSH terms
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Aged
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Angiotensin II / administration & dosage*
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Angiotensin II / therapeutic use
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Escherichia coli / isolation & purification
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Escherichia coli Infections / drug therapy
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Humans
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Intestinal Perforation / complications
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Intestinal Perforation / surgery
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Male
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Shock, Septic / complications*
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Shock, Septic / drug therapy
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Shock, Septic / microbiology
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Streptococcal Infections / drug therapy
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Streptococcus anginosus / isolation & purification
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Treatment Outcome
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Vasoplegia / drug therapy*
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Vasoplegia / etiology