Secondary prophylaxis of toxoplasmosis in pregnancy in an HIV-positive woman

Int J STD AIDS. 2018 Nov;29(11):1130-1132. doi: 10.1177/0956462418773955. Epub 2018 May 11.

Abstract

A 39-year-old HIV-positive black African woman with previously treated cerebral toxoplasmosis experienced a foetal intra-uterine death due to congenital toxoplasmosis. This case demonstrates the complexities of screening for maternal toxoplasmosis in the context of pregnancy and HIV infection-related cell-mediated immunosuppression. Additionally, the case highlights the challenges in providing effective preventative and therapeutic drug options for congenital toxoplasmosis.

Keywords: HIV; pregnancy; prevention; prophylaxis; toxoplasmosis.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / immunology
  • Adult
  • Female
  • Fetal Death
  • HIV Infections / complications*
  • HIV Infections / immunology
  • Humans
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious*
  • Toxoplasmosis / complications*
  • Toxoplasmosis / immunology*
  • Toxoplasmosis / transmission*
  • Toxoplasmosis, Cerebral
  • Toxoplasmosis, Congenital / congenital*