Location of the c-yes gene on the human chromosome and its expression in various tissues

Science. 1985 Mar 1;227(4690):1038-40. doi: 10.1126/science.2983418.

Abstract

Analysis of DNA from human embryo fibroblasts showed that ten Eco RI fragments were hybridizable with the Yamaguchi sarcoma virus oncogene (v-yes). Four of the Eco RI fragments were assigned to chromosome 18 and one to chromosome 6. There was evidence for multiple copies of yes-related genes in the human genome; however, only a single RNA species, 4.8 kilobases in length, was related to yes in various cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Avian Sarcoma Viruses / genetics
  • Base Sequence
  • Chromosome Mapping*
  • Chromosomes, Human, 16-18
  • Chromosomes, Human, 6-12 and X
  • DNA / genetics
  • Humans
  • Hybrid Cells / metabolism
  • Mice
  • Nucleic Acid Hybridization
  • Oncogenes*
  • Transduction, Genetic

Substances

  • DNA