Spillover of a hepatitis A outbreak among men who have sex with men (MSM) to the general population, the Netherlands, 2017

Ingrid Hm Friesema; Gerard Jb Sonder; Mariska Wf Petrignani; Annemarie E Meiberg; Gini Gc van Rijckevorsel; Wilhelmina Lm Ruijs; Harry Vennema

doi:10.2807/1560-7917.ES.2018.23.23.1800265

Spillover of a hepatitis A outbreak among men who have sex with men (MSM) to the general population, the Netherlands, 2017

Euro Surveill. 2018 Jun;23(23):1800265. doi: 10.2807/1560-7917.ES.2018.23.23.1800265.

Authors

Ingrid Hm Friesema¹, Gerard Jb Sonder², Mariska Wf Petrignani³, Annemarie E Meiberg³, Gini Gc van Rijckevorsel³, Wilhelmina Lm Ruijs³, Harry Vennema⁴

Affiliations

¹ Centre for Infectious Diseases, Epidemiology and Surveillance, Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
² Department of Infectious Disease Control, Public Health Service Amsterdam (GGD), Amsterdam, the Netherlands.
³ National Coordination Centre for Communicable Disease Control, Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
⁴ Centre for Infectious Diseases Research, Diagnostics and Screening, Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

PMID: 29897040
PMCID: PMC6152169
DOI: 10.2807/1560-7917.ES.2018.23.23.1800265

Abstract

Since 2015, outbreaks of hepatitis A among men who have sex with men (MSM) have been reported worldwide. To examine the impact of these MSM outbreaks in the Netherlands, we combined notification and epidemiological data with sequence analysis. Our results show the hazards of outbreaks within risk-groups spilling over into the largely susceptible general population. One third of the outbreak-related hepatitis A virus genotypes were detected in non-MSM cases.

Keywords: MSM; hepatitis A; outbreaks; spillover; surveillance.

MeSH terms

Adolescent
Adult
Aged
Child
Child, Preschool
DNA, Viral / genetics
Disease Notification / statistics & numerical data
Disease Outbreaks / statistics & numerical data*
Female
HIV Infections / epidemiology
Hepatitis A / diagnosis
Hepatitis A / epidemiology*
Hepatitis A / transmission
Hepatitis A Virus, Human / classification
Hepatitis A Virus, Human / genetics*
Hepatitis A Virus, Human / isolation & purification
Homosexuality, Male / statistics & numerical data*
Humans
Incidence
Infant
Male
Middle Aged
Netherlands / epidemiology
Sequence Analysis, DNA
Seroepidemiologic Studies
Young Adult

Substances

DNA, Viral