Prolactin, prolactin disorders, and dopamine agonists during pregnancy

Hormones (Athens). 2019 Jun;18(2):137-139. doi: 10.1007/s42000-018-0071-z. Epub 2018 Oct 19.

Abstract

Pituitary disorders, and especially prolactinomas, are not common among pregnant women, though they tend to occur during a woman's years of fertility. The majority of prolactinoma patients present with infertility and menstruation dysfunction; however, prolactinomas are associated with potentially significant morbidity if they remain unrecognized and untreated. Herein, we survey the role of prolactin and prolactinomas in pregnancy while also outlining the therapeutic approach to prolactinoma during pregnancy. The current literature on the impact of dopamine agonists during pregnancy is also reviewed.

Keywords: Dopamine agonists; Pregnancy; Prolactinoma.

Publication types

  • Review

MeSH terms

  • Dopamine Agonists / therapeutic use*
  • Female
  • Humans
  • Hyperprolactinemia / blood
  • Hyperprolactinemia / complications
  • Pituitary Neoplasms / blood
  • Pituitary Neoplasms / complications
  • Pituitary Neoplasms / drug therapy*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / blood
  • Pregnancy Complications, Neoplastic / drug therapy*
  • Pregnancy Outcome
  • Prolactin / blood*
  • Prolactin / physiology
  • Prolactinoma / blood
  • Prolactinoma / complications
  • Prolactinoma / drug therapy*
  • Treatment Outcome

Substances

  • Dopamine Agonists
  • Prolactin