Portable Ventilation/Perfusion Scanning is Useful for Evaluating Clinically Significant Pulmonary Embolism in the ICU Despite Abnormal Chest Radiography

J Intensive Care Med. 2020 Oct;35(10):1032-1038. doi: 10.1177/0885066618807859. Epub 2018 Oct 22.

Abstract

Objective: Computed tomography angiography is limited in the intensive care unit (ICU) due to renal insufficiency, hemodynamic instability, and difficulty transporting unstable patients. A portable ventilation/perfusion (V/Q) scan can be used. However, it is commonly believed that an abnormal chest radiograph can result in a nondiagnostic scan. In this retrospective study, we demonstrate that portable V/Q scans can be helpful in ruling in or out clinically significant pulmonary embolism (PE) despite an abnormal chest x-ray in the ICU.

Design: Two physicians conducted chart reviews and original V/Q reports. A staff radiologist, with 40 years of experience, rated chest x-ray abnormalities using predetermined criteria.

Setting: The study was conducted in the ICU.

Patients: The first 100 consecutive patients with suspected PE who underwent a portable V/Q scan.

Interventions: Those with a portable V/Q scan.

Results: A normal baseline chest radiograph was found in only 6% of patients. Fifty-three percent had moderate, 24% had severe, and 10% had very-severe radiographic abnormalities. Despite the abnormal x-rays, 88% of the V/Q scans were low probability for a PE despite an average abnormal radiograph rating of moderate. A high-probability V/Q for PE was diagnosed in 3% of the population despite chest x-ray ratings of moderate to severe. Six patients had their empiric anticoagulation discontinued after obtaining the results of the V/Q scan, and no anticoagulation was started for PE after a low-probability V/Q scan.

Conclusion: Despite the large percentage of moderate-to-severe x-ray abnormalities, PE can still be diagnosed (high-probability scan) in the ICU with a portable V/Q scan. Although low-probability scans do not rule out acute PE, it appeared less likely that any patient with a low-probability V/Q scan had severe hypoxemia or hemodynamic instability due to a significant PE, which was useful to clinicians and allowed them to either stop or not start anticoagulation.

Keywords: critical care; diagnostic imaging; hypoxia; massive pulmonary embolism; portable V/Q scan; pulmonary embolism; radiographic findings; respiratory failure; right ventricular failure; shock.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Critical Care / methods
  • Critical Care / statistics & numerical data
  • Critical Illness
  • Female
  • Humans
  • Intensive Care Units
  • Lung / diagnostic imaging
  • Male
  • Perfusion Imaging / methods
  • Perfusion Imaging / statistics & numerical data*
  • Point-of-Care Testing / statistics & numerical data*
  • Predictive Value of Tests
  • Probability
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Embolism / complications
  • Pulmonary Embolism / diagnostic imaging*
  • Radiography
  • Radionuclide Imaging / methods
  • Radionuclide Imaging / statistics & numerical data*
  • Respiration Disorders / diagnostic imaging*
  • Respiration Disorders / etiology
  • Retrospective Studies