Cutaneous Squamous Cell Carcinoma

Hematol Oncol Clin North Am. 2019 Feb;33(1):1-12. doi: 10.1016/j.hoc.2018.08.001.

Abstract

Cutaneous squamous cell carcinoma represents 20% of all skin cancers, resulting in 1 million cases in the United States each year. The lifetime risk of developing squamous cell carcinoma continues to increase annually and will likely continue to increase because of the aging population. Most cutaneous squamous cell carcinoma are treated locally, with a subset leading to recurrence, metastasis, and death. This review of cutaneous squamous cell carcinoma covers incidence, recurrence rates, mortality rates, risk factors, staging systems, treatment, prevention, and monitoring.

Keywords: Cutaneous squamous cell carcinoma; Diagnosis; Skin cancer; Treatment.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / etiology
  • Carcinoma, Squamous Cell / therapy*
  • Combined Modality Therapy
  • Disease Management
  • Disease Susceptibility
  • Genetic Predisposition to Disease
  • Humans
  • Incidence
  • Neoplasm Grading
  • Neoplasm Staging
  • Risk Factors
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / etiology
  • Skin Neoplasms / therapy*
  • Symptom Assessment
  • Treatment Outcome