Improving screening for malnourished children at high risk of death: a study of children aged 6-59 months in rural Senegal

Public Health Nutr. 2019 Apr;22(5):862-871. doi: 10.1017/S136898001800318X. Epub 2018 Dec 3.

Abstract

Objective: To investigate whether children with concurrent wasting and stunting require therapeutic feeding and to better understand whether multiple diagnostic criteria are needed to identify children with a high risk of death and in need of treatment.

Design: Community-based cohort study, following 5751 children through time. Each child was visited up to four times at 6-month intervals. Anthropometric measurements were taken at each visit. Survival was monitored using a demographic surveillance system operating in the study villages.

Setting: Niakhar, a rural area of the Fatick region of central Senegal.ParticipantsChildren aged 6-59 months living in thirty villages in the study area.

Results: Weight-for-age Z-score (WAZ) and mid-upper arm circumference (MUAC) were independently associated with near-term mortality. The lowest WAZ threshold that, in combination with MUAC, detected all deaths associated with severe wasting or concurrent wasting and stunting was WAZ <-2·8. Performance for detecting deaths was best when only WAZ and MUAC were used. Additional criteria did not improve performance. Risk ratios for near-term death in children identified using WAZ and MUAC suggest that children identified by WAZ <-2·8 but with MUAC≥115 mm may require lower-intensity treatment than children identified using MUAC <115 mm.

Conclusions: A combination of MUAC and WAZ detected all near-term deaths associated with severe anthropometric deficits including concurrent wasting and stunting. Therapeutic feeding programmes may achieve higher impact if WAZ and MUAC admission criteria are used.

Keywords: Anthropometry; Child survival; Mid-upper arm circumference; Mortality; Stunting; Therapeutic feeding; Underweight; Wasting.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anthropometry
  • Arm
  • Body Height
  • Body Weight
  • Child Nutrition Disorders / complications
  • Child Nutrition Disorders / diagnosis*
  • Child Nutrition Disorders / mortality
  • Child, Preschool
  • Cohort Studies
  • Female
  • Growth Disorders / complications
  • Growth Disorders / mortality*
  • Humans
  • Infant
  • Male
  • Malnutrition / complications
  • Malnutrition / diagnosis*
  • Malnutrition / mortality
  • Mass Screening / methods*
  • Risk Assessment
  • Risk Factors
  • Rural Population*
  • Senegal
  • Wasting Syndrome / complications
  • Wasting Syndrome / mortality*