Seroprevalence of HIV among pregnant women in Ethiopia: a systematic review and meta-analysis

Demeke Geremew; Fitsumbrhan Tajebe; Sintayehu Ambachew; Aklilu Endalamaw; Setegn Eshetie

doi:10.1186/s13104-018-4022-1

Seroprevalence of HIV among pregnant women in Ethiopia: a systematic review and meta-analysis

BMC Res Notes. 2018 Dec 19;11(1):908. doi: 10.1186/s13104-018-4022-1.

Authors

Demeke Geremew¹, Fitsumbrhan Tajebe², Sintayehu Ambachew³, Aklilu Endalamaw⁴, Setegn Eshetie⁵

Affiliations

¹ Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, University of Gondar, P.o.Box: 196, Gondar, Ethiopia. deme2112@gmail.com.
² Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, University of Gondar, P.o.Box: 196, Gondar, Ethiopia.
³ Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia.
⁴ Department of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
⁵ Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia.

Abstract

Objective: This systematic review and meta-analysis aimed to determine the pooled prevalence of HIV among pregnant women in Ethiopia.

Result: PubMed, EMBASE, Science Direct and Google scholar databases were searched to retrieve 15 relevant articles based on the inclusion criteria. A total of 13,746 participants were included in the original studies and considered in this analysis. Among subjects, 717 were infected with HIV only, and 12 were HIV-HBV co-infected pregnant women. In this meta-analysis, the pooled prevalence of HIV among pregnant women in Ethiopia was 5.74% (95% CI 3.96-7.53%). Regional analysis showed that 9.50% (95% CI 7.76-11.23%) in Amhara, 4.80% (95% CI 3.12-6.49%) in Addis Ababa, 2.14% (95% CI - 0.54 to 4.82%) in SNNP and 4.48% (95% CI 2.56-6.41%) in Oromia region. Besides, six studies reported HIV-HBV co-infection and the pooled prevalence was 0.68% (95% CI 0.27-1.08%) among pregnant women in Ethiopia.

Keywords: Ethiopia; HIV; Meta-analysis; Pregnant women; Systematic review.

Publication types

Meta-Analysis
Systematic Review

MeSH terms

Adult
Ethiopia / epidemiology
Female
HIV Infections / epidemiology*
HIV Seroprevalence*
Humans
Pregnancy
Pregnancy Complications, Infectious / epidemiology*
Young Adult