A single-center analysis of early readmission after renal transplantation

Clin Transplant. 2019 May;33(5):e13520. doi: 10.1111/ctr.13520. Epub 2019 Mar 27.

Abstract

Background: Thirty-day readmission rates (early hospital readmission, EHR) are an important benchmark for quality improvement. Nationally, patients undergoing renal transplantation incur a 31% EHR rate. While national databases provide useful data, the impact of EHR on individual centers has received little attention. We proposed that an institutional review of EHR after renal transplantation may provide a benchmark for individual transplant programs and identify modifiable program-specific issues to reduce EHR.

Methods: We reviewed 269 consecutive kidney transplant recipients over a five-year period (2012-2016). Early hospital readmission was modeled using generalized linear modeling assuming a binary distribution.

Results: About 21% of patients were readmitted within 30 days. Deceased kidney donation (DD), delayed graft functioning (DGF), anti-thymocyte globulin (ATG) induction, diabetes, public insurance, weekend discharge, and low glomerular filtration rate (eGFR) at discharge were all identified as risk factors for readmission. Early hospital readmission was not correlated with risk of death (5.4% at 44 months: HR 2.2 (95% CI [0.7, 6.6]; P = 0.1473) or graft loss.

Conclusions: EHR after renal transplantation is common. Certain factors may predict an increased risk for EHR. A multi-disciplinary approach to discharge planning may limit some EHR, but most complications and adverse events are unpredictable and require hospital-level of care.

Keywords: care delivery; hospital readmission; kidney (allograft) function / dysfunction; kidney disease; kidney transplantation: living donor; quality of care.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Antilymphocyte Serum / analysis
  • Delayed Graft Function / physiopathology*
  • Female
  • Follow-Up Studies
  • Glomerular Filtration Rate
  • Humans
  • Kidney Failure, Chronic / surgery*
  • Kidney Function Tests
  • Kidney Transplantation / methods*
  • Living Donors / supply & distribution*
  • Male
  • Middle Aged
  • Patient Readmission / statistics & numerical data*
  • Postoperative Complications*
  • Prognosis
  • Risk Factors

Substances

  • Antilymphocyte Serum