A novel treatment for idiopathic knuckle pads with cantharidin-podophylotoxin-salicylic acid

Pediatr Dermatol. 2019 Jul;36(4):544-545. doi: 10.1111/pde.13803. Epub 2019 Mar 18.

Abstract

Knuckle pads are benign subcutaneous nodules that appear most frequently on the small joints of the hands. In children, they are often idiopathic, and no universally effective treatment has been reported. We present the case of an adolescent successfully treated with a combination of topical cantharidin -podophylotoxin -salicylic acid.

Keywords: benign neoplasm; topical therapy.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Adolescent
  • Cantharidin / therapeutic use*
  • Dermoscopy / methods
  • Drug Therapy, Combination
  • Finger Joint / physiopathology
  • Follow-Up Studies
  • Hand Dermatoses / diagnosis
  • Hand Dermatoses / drug therapy
  • Humans
  • Male
  • Podophyllotoxin / therapeutic use*
  • Salicylic Acid / therapeutic use*
  • Skin / drug effects
  • Skin / pathology*
  • Treatment Outcome

Substances

  • Cantharidin
  • Podophyllotoxin
  • Salicylic Acid