Seizures and myoclonus in patients with Alzheimer's disease

Neurology. 1986 Sep;36(9):1226-30. doi: 10.1212/wnl.36.9.1226.

Abstract

We reviewed 81 patients with dementia and autopsy findings of Alzheimer's disease (AD) to identify patients with seizures or myoclonus after onset of dementia. Eight (10%) had seizures, and eight others (10%) had myoclonus. The incidence of seizures was 10 times more than expected in a reference population. Seizures occurred in any stage of AD, but myoclonus was often a late manifestation. Both seizures and myoclonus, individually or together, are manifestations of AD and may be seen at any time in the course of the illness.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Alzheimer Disease / complications*
  • Epilepsies, Myoclonic / complications*
  • Humans
  • Middle Aged
  • Seizures / complications*