Pediatric Tubercular Meningitis: A Review

J Pediatr Neurosci. 2018 Oct-Dec;13(4):373-382. doi: 10.4103/JPN.JPN_78_18.

Abstract

Childhood tuberculosis (TB) has a high incidence and prevalence in developing countries like India with tubercular meningitis (TBM) being the most common cause of death. Most cases of TBM are diagnosed late when despite adequate therapy; morbidity and mortality continue to remain high. This review aims to provide a pragmatic approach at dealing with cases of tubercular meningitis in children including clinical features, laboratory and radiological criteria, treatment options and prognostic implications. The objective of this review is to assist in early identification, proper investigation and timely treatment of TBM in children in order to reduce neurological morbidity and mortality associated with it.

Keywords: Antitubercular therapy; tubercular meningitis; tuberculosis; ventriculoperitoneal shunt.

Publication types

  • Review