Streptococcal Toxic Shock Syndrome After Insertion of a Levonorgestrel Intrauterine Device

J Obstet Gynaecol Can. 2019 Dec;41(12):1772-1774. doi: 10.1016/j.jogc.2019.02.017. Epub 2019 Apr 10.

Abstract

Background: The insertion of intrauterine devices (IUDs) is associated with a small increased risk of pelvic inflammatory disease and ascending infection, particularly in patients with risk factors. However, the risk of sepsis and toxic shock syndrome after insertion of an IUD is a rare event, described only through case reports in the literature.

Case: This report describes the case of a 40-year-old woman who presented with high fever, myalgias, and abdominal pain 2 days following the insertion of a levonorgestrel-releasing IUD. She was found to have group A Streptococcus infection in the vagina that led to a diagnosis of streptococcal toxic shock syndrome and required admission to the intensive care unit.

Conclusion: Toxic shock syndrome is a rare but potentially catastrophic complication after the insertion of an IUD. Health care providers should be conscious of this complication, particularly among patients presenting with fever and sepsis soon after IUD insertion.

Keywords: Toxic shock syndrome; levonorgestrel intrauterine device; streptococcus.

Publication types

  • Case Reports

MeSH terms

  • Acute Lung Injury / etiology
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Female
  • Humans
  • Immunoglobulins, Intravenous / adverse effects
  • Intrauterine Devices, Medicated / adverse effects*
  • Shock, Septic / drug therapy
  • Shock, Septic / microbiology*
  • Streptococcal Infections / microbiology*
  • Streptococcal Infections / therapy
  • Streptococcus pyogenes / isolation & purification*

Substances

  • Anti-Bacterial Agents
  • Immunoglobulins, Intravenous