Towards a cancer-chemopreventive diet

Nat Biomed Eng. 2018 Jan;2(1):6-7. doi: 10.1038/s41551-017-0186-6.

Abstract

Commensal microbes engineered to convert natural compounds found in cruciferous vegetables into molecules with anticancer properties prevent carcinogenesis and cause the regression of colorectal cancer in mice fed with a vegetable diet.

Publication types

  • News

MeSH terms

  • Animals
  • Anticarcinogenic Agents / administration & dosage*
  • Biological Availability
  • Chemoprevention / methods*
  • Colorectal Neoplasms / microbiology*
  • Colorectal Neoplasms / prevention & control*
  • Escherichia coli / enzymology*
  • Gastrointestinal Microbiome*
  • Glucosinolates / administration & dosage
  • Glucosinolates / metabolism
  • Isothiocyanates / administration & dosage
  • Isothiocyanates / metabolism
  • Mice, Inbred BALB C

Substances

  • Anticarcinogenic Agents
  • Glucosinolates
  • Isothiocyanates
  • sulphoraphene