Case Report: Bilateral Granulomatous Anterior Uveitis in HIV-patient with Disseminated Talaromycosis (penicilliosis) Marneffei Infection

Ocul Immunol Inflamm. 2020 Oct 2;28(7):1066-1068. doi: 10.1080/09273948.2019.1657468. Epub 2019 Oct 2.

Abstract

We report on a 22-years-old Thai male patient with congenital HIV infection. Due to his non-adherence to antiretroviral treatment he developed disseminated Talaromyces marneffei infection and was treated with intravenous amphotericin B. Despite this treatment, he presented with bilateral granulomatous anterior uveitis. Uveitis improved only after intracameral injection of amphotericin B.

Keywords: Granulomatous anterior uveitis; HIV; Penicilliosis; Talaromyces marneffei; intracameral amphotericin B.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Anterior Chamber / drug effects
  • Antifungal Agents / therapeutic use
  • Fungemia / diagnosis*
  • Fungemia / drug therapy
  • Fungemia / microbiology
  • Granuloma / diagnosis*
  • Granuloma / drug therapy
  • Granuloma / microbiology
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy
  • HIV Infections / microbiology
  • Humans
  • Male
  • Mycoses / diagnosis*
  • Mycoses / drug therapy
  • Mycoses / microbiology
  • Talaromyces / isolation & purification*
  • Uveitis, Anterior / diagnosis*
  • Uveitis, Anterior / drug therapy
  • Uveitis, Anterior / microbiology
  • Young Adult

Substances

  • Antifungal Agents
  • Amphotericin B

Supplementary concepts

  • Talaromyces marneffei
  • talaromycosis