An Endotracheal Plasmablastic Lymphoma

Respiration. 2019;98(6):546-550. doi: 10.1159/000503586. Epub 2019 Oct 21.

Abstract

We describe an exceptionally rare case of a male patient with newly diagnosed advanced human immunodeficiency virus (HIV) infection, who presented with a plasmablastic lymphoma involving the right maxillary alveolar ridge with associated cervical lymphadenopathy. On a staging positron emission tomography computed tomography (PET-CT) scan, he was incidentally found to have an endotracheal tumour involving the anterolateral aspect of the mid-trachea. The tumour appeared to be well-vascularised at bronchoscopy and was confirmed as well-differentiated plasmablastic lymphoma. Plasmablastic lymphoma is a rare form of non-Hodgkin lymphoma and is associated with HIV. Tracheal involvement to the extent seen in our patient is exceptionally rare, and, to the best of our knowledge, has never been described.

Keywords: Endotracheal tumour; PET-CT scan; Plasmablastic lymphoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols
  • Biopsy, Needle
  • Bronchoscopy / methods
  • Combined Modality Therapy
  • Follow-Up Studies
  • HIV Infections / complications
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy
  • Humans
  • Immunohistochemistry
  • Male
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Plasmablastic Lymphoma / complications
  • Plasmablastic Lymphoma / diagnostic imaging*
  • Plasmablastic Lymphoma / pathology
  • Plasmablastic Lymphoma / therapy*
  • Positron Emission Tomography Computed Tomography / methods
  • Radiotherapy, Adjuvant
  • Rare Diseases
  • Tracheal Neoplasms / complications
  • Tracheal Neoplasms / diagnostic imaging*
  • Tracheal Neoplasms / pathology
  • Tracheal Neoplasms / therapy*
  • Treatment Outcome