Role of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis and Management of Mediastinal Cyst

J Bronchology Interv Pulmonol. 2020 Apr;27(2):142-146. doi: 10.1097/LBR.0000000000000640.

Abstract

Background: Foregut cysts account for >50% of cystic lesions in the mediastinum, of which bronchogenic cysts are most common. Surgical resection is the most definitive approach for its diagnosis and treatment. A recent systematic review, however, suggests that endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has a role in the management of bronchogenic cyst. We report our experience with EBUS-TBNA in the diagnosis and management of bronchogenic cysts.

Methods: Medical records of patients with evidence of mediastinal cysts who underwent EBUS-TBNA between 2008 and 2016 were reviewed.The primary aims of this study were to assess EBUS-TBNA diagnostic yield of peri-bronchial cysts and their specific type/origin and to determine its short-term and long-term drainage efficacy.

Results: A total of 26 patients met the inclusion criteria. The cytopathology diagnosis was compatible with bronchogenic cyst in 4 cases, pleural-pericardial cyst in 3 cases, and 19 were indeterminate cysts. Successful long-term treatment occurred in 5.5% of the subjects. One patient developed inflammatory pericarditis after EBUS-TBNA.

Conclusion: Diagnostic and therapeutic yield of EBUS-TBNA for mediastinal cysts is limited and surgical resection remains the treatment of choice.

MeSH terms

  • Bronchogenic Cyst / pathology*
  • Bronchogenic Cyst / surgery
  • Drainage / methods
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration / adverse effects
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Image-Guided Biopsy / instrumentation*
  • Male
  • Mediastinal Cyst / diagnostic imaging
  • Mediastinal Cyst / pathology*
  • Mediastinal Cyst / surgery
  • Middle Aged
  • Pericarditis / etiology
  • Pericarditis / pathology
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Ultrasonography / methods