Genetic instruments with too many strings: acknowledging pleiotropy and population structure in Mendelian randomization studies
Eur Heart J
.
2020 Feb 14;41(7):892-893.
doi: 10.1093/eurheartj/ehz943.
Authors
Jeremy A Labrecque
1
,
Jay S Kaufman
2
,
Jonathan Y Huang
3
Affiliations
1
Department of Epidemiology, Erasmus MC, Dr. Molewaterplein 50, 3015 GE Rotterdam, the Netherlands.
2
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 1020 Avenue des Pins Ouest, H3A 1A2 Montreal, Quebec, Canada.
3
Department of Biostatistics, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), 117609, Singapore.
PMID:
31960031
DOI:
10.1093/eurheartj/ehz943
No abstract available
Publication types
Comment
MeSH terms
Coronary Disease*
Genetic Pleiotropy
Genetic Variation
Humans
Mendelian Randomization Analysis*