Effect of Metabolic Syndrome on Blood Pressure Changes During Cataract Surgery

Asia Pac J Ophthalmol (Phila). 2020 Jan-Feb;9(1):14-19. doi: 10.1097/01.APO.0000617932.60445.77.

Abstract

Purpose: To investigate effect of metabolic syndrome on blood pressure during cataract surgery with topical anesthesia.

Design: A single-centered, retrospective case series.

Methods: Consecutive patients who were hospitalized and underwent phacoemulsification and insertion of intraocular lens with topical anesthesia in October 2016 were included. Perioperative blood pressure and pulse pressure were compared between patients with metabolic syndrome (metabolic group) and sex- and age-matched patients without metabolic syndrome (nonmetabolic group) at six time points: on admission, in the morning of the operation, 2 hours before the operation, at the point of entering the operation room, during the operation, and after the operation. Perioperative use of etizolam and nicardipine was compared between the two groups.

Results: Thirty patients in the metabolic group and 30 in the nonmetabolic group were included. There was no difference in changes compared with the values on admission in systolic pressure and pulse pressure at any examination point between the two groups. There was no difference in changes in diastolic pressure between the two groups, except for at 2 hours before the operation (1.4 ± 9.6 mm Hg in the metabolic group vs -6.2 ± 8.5 mm Hg in the nonmetabolic group; P = 0.044). The number of patients who were administered etizolam was 5/30 (16.7%) in the metabolic group and 2/30 (6.7%) in the nonmetabolic group, showing no significant difference. No patients were administered intravenous nicardipine in either group.

Conclusions: Well-controlled metabolic syndrome did not affect the changes in perioperative blood pressure during cataract surgery with topical anesthesia.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Pressure / physiology*
  • Diazepam / administration & dosage
  • Diazepam / analogs & derivatives
  • Female
  • Humans
  • Intraocular Pressure / physiology
  • Lens Implantation, Intraocular*
  • Male
  • Metabolic Syndrome / physiopathology*
  • Middle Aged
  • Phacoemulsification*
  • Retrospective Studies
  • Tranquilizing Agents / administration & dosage

Substances

  • Tranquilizing Agents
  • etizolam
  • Diazepam