Coronavirus disease (COVID-19) and neonate: What neonatologist need to know

J Med Virol. 2020 Jun;92(6):564-567. doi: 10.1002/jmv.25740. Epub 2020 Mar 12.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause china epidemics with high morbidity and mortality, the infection has been transmitted to other countries. About three neonates and more than 230 children cases are reported. The disease condition of the main children was mild. There is currently no evidence that SARS-CoV-2 can be transmitted transplacentally from mother to the newborn. The treatment strategy for children with Coronavirus disease (COVID-19) is based on adult experience. Thus far, no deaths have been reported in the pediatric age group. This review describes the current understanding of COVID-19 infection in newborns and children.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Angiotensin-Converting Enzyme 2
  • Betacoronavirus / drug effects
  • Betacoronavirus / pathogenicity*
  • COVID-19
  • Cell Line
  • Child
  • Child, Preschool
  • China / epidemiology
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / transmission
  • Disease Management
  • Fluid Therapy / methods
  • Humans
  • Infant
  • Nitric Oxide / therapeutic use
  • Pandemics*
  • Peptidyl-Dipeptidase A / metabolism
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / drug therapy
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / transmission
  • Protein Binding
  • Pulmonary Surfactants / therapeutic use
  • SARS-CoV-2
  • Spike Glycoprotein, Coronavirus / metabolism

Substances

  • Pulmonary Surfactants
  • Spike Glycoprotein, Coronavirus
  • spike protein, SARS-CoV-2
  • Nitric Oxide
  • Peptidyl-Dipeptidase A
  • ACE2 protein, human
  • Angiotensin-Converting Enzyme 2