Pilomotor Seizures in a Patient With LGI1 Encephalitis

Jinxia Yang; Qiying Sun; Guang Yang

doi:10.3389/fneur.2020.00061

Pilomotor Seizures in a Patient With LGI1 Encephalitis

Front Neurol. 2020 Feb 20:11:61. doi: 10.3389/fneur.2020.00061. eCollection 2020.

Authors

Jinxia Yang¹, Qiying Sun¹, Guang Yang²

Affiliations

¹ Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China.
² Department of Emergency, Xiangya Hospital, Central South University, Changsha, China.

Abstract

Limbic encephalitis (LE) with antibodies against leucine-rich glioma inactivated protein 1 (LGI1) is an autoimmune disease with variable clinical features, including seizures, cognitive disorders, psychiatric disturbances, and hyponatremia. The majority of these patients present faciobrachial dystonic seizures (FBDS), which are regarded as a characteristic symptom. A few cases have reported pilomotor seizures as the main manifestation of anti-LGI1 encephalitis. Here, we described a Chinese woman with frequent pilomotor seizures who was finally diagnosed as having anti-LGI1 encephalitis. Our report emphasizes the possible significance of pilomotor seizures in anti-LGI1 encephalitis.

Keywords: anti-LGI1 antibody; case report; faciobrachial dystonic seizures; limbic encephalitis; pilomotor seizures.

Publication types

Case Reports