A Unique Case of Acquired Hemophilia A Presenting with Transient Ischemic Attack

Acta Haematol. 2021;144(1):88-90. doi: 10.1159/000506273. Epub 2020 Mar 10.

Abstract

Acquired hemophilia A (AHA) is a rare but serious condition, usually associated with significant spontaneous or traumatic bleeding and a high mortality rate. In this report, we describe the case of an elderly patient presenting a transient ischemic attack concurrently with AHA. A thrombotic event in AHA is occasionally associated with the use of bypassing agents for treatment, but a spontaneous thrombotic event has not ever been described.

Keywords: Acquired hemophilia A; Coagulation; Hemostasis; Stroke.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Biomarkers
  • Blood Coagulation
  • Blood Coagulation Tests
  • Diagnosis, Differential
  • Factor VIII / administration & dosage
  • Factor VIII / therapeutic use
  • Hemophilia A / diagnosis*
  • Hemophilia A / etiology
  • Hemophilia A / therapy
  • Humans
  • Ischemic Attack, Transient / diagnosis*
  • Ischemic Attack, Transient / etiology
  • Ischemic Attack, Transient / therapy
  • Male
  • Recombinant Proteins / administration & dosage
  • Recombinant Proteins / therapeutic use
  • Symptom Assessment
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Biomarkers
  • Recombinant Proteins
  • Factor VIII