1 Department of Paediatrics, Division of Paediatric Critical Care Medicine, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. m.c.j.kneyber@umcg.nl.
2 Critical Care, Anaesthesiology, Perioperative & Emergency Medicine (CAPE), University of Groningen, Groningen, the Netherlands. m.c.j.kneyber@umcg.nl.
3 Pediatric Acute Lung Injury and Sepsis Investigators, Durham, NC, USA.
4 Family and Community Health, School of Nursing, Anesthesia and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
5 Research Institute, Children's Hospital of Philadelphia, Philadelphia, PA, USA.