SARS Cov-2 infection in a renal-transplanted patient: A case report

Am J Transplant. 2020 Jul;20(7):1882-1884. doi: 10.1111/ajt.15902. Epub 2020 May 10.

Abstract

The clinical manifestation of COVID-19 can vary from an asymptomatic course to ARDS requiring invasive mechanical ventilation and extracorporeal membrane oxygenation. A kidney transplanted patient infected with SARS CoV-2 infection showed a mild disease despite immune suppression. It is possible that Immunosuppression can "be protective" as the cytokine storm is an important factor in the disease story. Despite the good outcome reported in the present case report, is remains of vital importance the solid organ transplant patients use precautions in order to avoid the infection.

Keywords: clinical research/practice; immunosuppressant - calcineurin inhibitor: tacrolimus; infection and infectious agents - viral; infectious disease.

Publication types

  • Case Reports

MeSH terms

  • Betacoronavirus
  • COVID-19
  • Ceftriaxone / administration & dosage
  • Coronavirus Infections / complications*
  • Coronavirus Infections / therapy*
  • Cytokines / metabolism
  • Glomerulonephritis, IGA / complications*
  • Glomerulonephritis, IGA / surgery
  • Humans
  • Immunosuppression Therapy / adverse effects
  • Immunosuppression Therapy / methods
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation*
  • Male
  • Middle Aged
  • Mycophenolic Acid / administration & dosage
  • Pandemics
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / therapy*
  • SARS-CoV-2
  • Tacrolimus / administration & dosage
  • Treatment Outcome

Substances

  • Cytokines
  • Ceftriaxone
  • Mycophenolic Acid
  • Tacrolimus