SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission

Transfusion. 2020 Jun;60(6):1119-1122. doi: 10.1111/trf.15841. Epub 2020 May 27.

Abstract

Oral swabs, sputum, and blood samples from 18 asymptomatic and symptomatic patients with SARS-CoV-2 infection were examined using RT-PCR testing in order to assess the risk of transfusion-related transmission. In asymptomatic patients as well as patients with flu-like symptoms and fever, no SARS-CoV-2 RNA could be detected in the blood or serum despite a clearly positive result in all throat swabs. As patients with symptoms of infectious disease will not be admitted to blood donation, the risk for transfusion transmission of SARS-CoV-2 seems to be negligible.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Asymptomatic Infections*
  • Betacoronavirus / isolation & purification*
  • Blood Donors*
  • Blood Safety*
  • COVID-19
  • Coronavirus Infections / blood
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / transmission*
  • Donor Selection*
  • Female
  • Germany
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / blood
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / transmission*
  • SARS-CoV-2
  • Transfusion Reaction / prevention & control*
  • Transfusion Reaction / virology
  • Young Adult