Objectives: To describe the CT features and clinical characteristics of pediatric patients with coronavirus disease 2019 (COVID-19).
Methods: A total of 9 COVID-19 infected pediatric patients were included in this study. Clinical history, laboratory examination, and detailed CT imaging features were analyzed. All patients underwent the first CT scanning on the same day of being diagnosed by real-time reverse-transcription polymerase chain reaction (rRT-PCR). A low-dose CT scan was performed during follow-up.
Results: All the child patients had positive results. Four patients had cough and one patient had fever. One patient presented both cough and fever. Two children presented other symptoms like sore throat and stuffy nose. One child showed no clinical symptom. Five patients had positive initial CT findings with subtle lesions like ground-glass opacity (GGO) or spot-like mixed consolidation. Three patients were reported with negative results in the initial and follow-up CT examination. One patient was reported with initial negative CT findings but turning positive during the first follow-up. All patients had absorbed lesions on follow-up CT images after treatment.
Conclusions: Pediatric COVID-19 patients have certain imaging and clinical features as well as disease prognosis. Children with COVID-19 tend to have normal or subtle CT findings and relatively better outcome.
目的: 探讨9例儿童2019冠状病毒病(coronavirus disease 2019，COVID-19)患者的临床及影像学特征。方法: 入组9例COVID-19患儿。收集患儿的临床病史、症状及体征、实验室指标。患儿均行咽拭子实时反转录聚合酶链反应(real-time reverse-transcription polymerase chain reaction，rRT-PCR)检查进行确诊，于同一天行首诊CT检查，并于治疗后行随访CT检查。分析患儿的临床及影像学特征。结果: 9例患儿均经咽拭子rRT-PCR检查确诊COVID-19，临床症状相对较轻。5名患儿的首诊CT影像学表现即有阳性发现。3名患儿首诊及随访CT影像学表现均为阴性。1名患儿首诊CT影像学表现为阴性，首次随访CT影像学表现显示出现新发病灶。CT影像有阳性发现的患儿复查CT影像学表现均提示病灶较前有不同程度的吸收。结论: 儿童COVID-19患者的临床及影像学表现具有一定特点。COVID-19患儿的影像学表现正常或较轻，且预后相对良好。.
Keywords: children; computerized tomography; coronavirus disease 2019; pneumonia.