Synchronous symptomatic parathyroid carcinoma and parathyroid adenoma with incidental follicular thyroid carcinoma

Ann R Coll Surg Engl. 2020 Oct;102(8):e192-e195. doi: 10.1308/rcsann.2020.0101. Epub 2020 May 21.

Abstract

We describe the case of an 89-year old Caucasian woman admitted with confusion and severe clinical manifestations of acute hypercalcaemia. There was no history suggestive of any malignancy and initial management included correction of the hypercalcaemia with intravenous fluid therapy. Sestamibi parathyroid scintigraphy and neck ultrasonography demonstrated a 4cm left-sided thyroid lesion and a nearly 2cm right-sided thyroid lesion. The patient underwent a total thyroidectomy and parathyroidectomy. Histology confirmed a concomitant parathyroid adenoma, parathyroid carcinoma and follicular thyroid carcinoma. To our knowledge, this is the first reported case in the literature.

Keywords: Follicular thyroid carcinoma; Parathyroid carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Follicular*
  • Aged, 80 and over
  • Female
  • Humans
  • Hypercalcemia / etiology
  • Parathyroid Glands / diagnostic imaging
  • Parathyroid Glands / pathology
  • Parathyroid Glands / surgery
  • Parathyroid Neoplasms*
  • Parathyroidectomy
  • Radionuclide Imaging
  • Thyroid Gland / diagnostic imaging
  • Thyroid Gland / pathology
  • Thyroid Gland / surgery
  • Thyroid Neoplasms*
  • Thyroidectomy