Clinical and Epidemiological Features of a Family Cluster of Symptomatic and Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection

J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):362-365. doi: 10.1093/jpids/piaa060.

Abstract

In a family experiencing coronavirus disease 2019, the parents and 2 children aged 2 and 5 years became infected but the youngest child was not infected. Both children initially shed infectious virus, but cleared the virus after 5 to 6 days in the nasopharynx. However, viral RNA was continuously detected in the children's stool for more than 4 weeks.

Keywords: COVID-19; RNA persistence; SARS-CoV-2; children; gastrointestinal.

MeSH terms

  • Adult
  • Betacoronavirus*
  • COVID-19
  • Child, Preschool
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / pathology*
  • Coronavirus Infections / transmission
  • Family*
  • Female
  • Germany / epidemiology
  • Humans
  • Infant
  • Infectious Disease Incubation Period
  • Male
  • Nasopharynx / virology
  • Pandemics
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / pathology*
  • Pneumonia, Viral / transmission
  • SARS-CoV-2
  • Viral Load
  • Virus Shedding